BioMonstration (english version)

XavCC
May 17

A translation of the original French version, by its author.

In a (spell) cast of desires of sorts of wacky self-ethnography I had decided to throw on walls a little description of my practices in garage biology. The #BioMonstration quickly became a signature as a marker to this loose thread, a beacon in the formulation of my thoughts.

A graffiti that emerges without coherence of frequency when at the same time an urge to share meets a belief, or a hope, that I can describe simply as a small piece of something bigger.

Rather than forcing a restructuring of this proto canvas, I wish to transcribe it here such as it pours from my imagination onto walls of the Internet. In the order in which appeared these emanations of a pseudo disorder, of an obscurity or a fog perceived by the uninitiated person.

June, 23, 2021

It’s when you correct a sequence in your sequence of a piece of the living.

Not to be confused with slaughtering

Demonym of people who inhabit the laboratory department.

A bit like a Hi-Fi tech ( High fidelity) system framed to see non-chromosomal DNA, often provided by bacteria or in baker’s yeast.

Bacteria and yeast that humans spread all over their plasma screens.

Ethnonym for a group of people living outside the disciplinary cell of biology, sometimes keen to enter it.

Ethnonym of a group of people who broke into the disciplinary cell of biology and who striving to smash chains, walls, and bars.

Formulation with digit encryption like of the CAFFEINE by the disciplinary cell of chemistry. This one probably thinking that cipher quality would offer enough safety to keep the said substance at home safely.
(YouHaveBeenPwnd)


June, 24, 2021

I tell myself that I can continue this thread with a #BioMonstration with the intention of micro-narration a little differently from practices in the study and manipulation of the living.

Sort of (auto)ethnography peppered with fabulation

Before the continuations, hop the ears in Bio Is The New Black: Design embarked in a laboratory of biology
https://cpu.dascritch.net/post/2021/06

Note:
it is mentioned in the episode that Design could have as first historical emergence the year 1750

the word and concept biology was forged in 1766 by Michael Christoph Hanow; then in 1797 by the doctors Roose, Burdach and Treviranus (1800 -1802) then by Lamarck (1800 - 1802) naturalist, botanist, zoologist.

As a scientific discipline.

“The positivist in biology avoids metaphysical concepts by performing a reduction in his questions. Thus, when François Jacob declares that “life” is no longer studied in laboratories, one can understand that the concept of “life” is similar to the old abstractions of metaphysics. What happens in the laboratories? We study redox relationships, methylations, different reactions between molecules: but do we ever see “life”? Instead of “life”, positive biology studies the properties of one of the levels of organization characteristic of living organisms (individuals, products, cells, molecules).
One could call up other examples: does biology study “the animal” or does it study the action-reaction sequences, reflexes, stereotyped behaviors? Does it study “the human” or only its physiology, its social behaviors?”

Metaphysics and biology, by Thierry Hocquet in précis de biologie
https://fr.calameo.com/read/000015856d


Place for experiments and manipulation in the bathroom of people from the DIY / garage / hacking biology communities

“we extracted and sequenced a DNA in the wetlab”

Thanks to @kaerhon for clarifying this important point

Lavaboratory illustrated in pictures

3eb0605e9ca7110a


It’s Monday, I tidied up and cleaned my bench to get back to work.

A work surface that in biohacking / biopunk / #diybio you struggle to do yourself, then becomes one of your most frequent work areas.

Does it hardly bear its qualifier of “plane” so much it plays and unfolds phenomena and events that destabilize, even crush, many of our established plans?

Who is haunting whom?

I often think about it at night, sometimes I feel trapped in its dithering.

“Large canvas envelope, usually filled with straw, with which a bed was lined.”

There is not a prisoner who does not turn over in the evening on his straw mattress at the thought that the dawn may be sinister, who does not fall asleep without wishing that nothing would happen. - (Henri Alleg, The Question, 1957)

https://en.wiktionary.org/wiki/paillasse

Monstration could have a double semantic origin in Latin with a double meaning.

Monstratio: direction, guidance, indication, hint

https://en.wiktionary.org/wiki/monstratio

MONSTRO, AS, ARE, AVI, ATUM: to show, to make see in a precise manner. To indicate.

The thing that is indicated, pointed out, with the finger.

And also monstrum: an unexpected fact that may be interpreted as a “warning” from a higher power. And monstrosus, which means bizarre, even deformed.


Clogged laundromat, bunged lavaboratory

Contaminated Petri dish

Poor Microscopy

Incubator that breaks down

Missed insertion of modified plasmid

Etc

The malfunction, the bug, the breakdown, the ‘disobedience’, the strike or more generally the ‘accident’ (in Virilio’s words) are generators of saturated spaces (of messages, of pollutions) each fulfilling a fairly precise function. Starting with allowing one to get out of a state of stupor, to ‘get going’, to un/tangle oneself (thanks to Olivier Ertzscheid)

It is also an opportunity to reconfigure ourselves collectively

For example, at a 2-day biohacking workshop in a library… Right from the start, one of the devices was broken.

This opportunity was seized by people not initially interested in the workshop, and with profiles very different from the initial participants, to insert themselves into the group and to “twist” the initial “programme” (march) of the workshop to make it their own and to give it a new function / purpose.

7 October 2021: to be continued

25 October 2021

Sending plasmids, passionately prepared and packaged on a heat-screw machine in free material

On a small piece of paper… heading for Ukraine.

This manipulation brings back memories of a Pasteur Institute from the 1920s that we never knew.

We dodge borders, customs. The mark is invisible after drying.

They are even little Frankensteins (sic) for some people who have not yet discovered and practiced, not yet experienced in their flesh.

This aesthetic of the stamped letter allows us to pass under the radar.

Our gesture folds into itself and on an infinitesimal layer an immeasurable quantity of time, technique and acquired knowledge.

It also requires a new critical thinking about correspondence and letters to emerge and develop.

Enclosed, annotated, the plasmid will travel to a new adventure.

fe8d57920cf104ba
6a3be7f530de71a4
b9534bbf24b1343f

5 November 2021

Messenger ribonucleic acid carrying something, when at some point in transcription the pre-messenger RNA escapes from inside the RNA polymerase complex (“away, to the right, fleeing fate”), which gets added to it by an enzyme, this is RNA guanylyltransferase which adds a guanosine (G) on the 5’ end.

This cap has several purposes

Who comes to my salon, my garage, or my lavaboratory to do a cap[1] haircut?

Come and watch the hairdressing or scissor day!

https://en.wikipedia.org/wiki/Five-prime_cap

6 November 2021

(Field: Biology/Biochemistry and Molecular Biology.)

Definition:

DNA that propagates through the genome using proteins encoded by other gene sequences, with no immediately visible benefit to the organism. More accurate: Selfish genetic element

Note:

  1. selfish DNA has the ability to maintain, accumulate and transpose itself.

  2. sometimes the term “junk DNA” is still used, or selfish genetic elements and their silencers

Foreign equivalent: ADN poubelle, ADN égoïste, ADN non-codant unique

This “junk” DNA, that part of the genome which at first glance serves no purpose (the kind that pisses off capitalistic productivists?), well, actually plays an important role in epigenetic processes.

Vocabulary of biology at LégiFrance (2012)

https://www.legifrance.gouv.fr/jorf/id/JORFTEXT000025990940/

Let’s think about Barbara McClintock, who made this discovery, and one of the 58 women (including Marie Curie twice, and her daughter Irène Joliot-Curie once) who won the Nobel Prize (1983 medicine and physiology), compared with 885 men.

Who am I? What invisible others make me what I am?

My body is made up of about 10 to 100 times more bacterial cells than human cells.

I am 10 times more non-human genes than human genes!

I am billions of billions of bacteria, fungi and spores, parasites and micro-insects, viruses, yeasts, archaea… On me and deep inside me.

I am alive through and with the lives of others.


  1. certificate of professional competence (CAP), or 5’-cap ↩︎